Risk factors for recurrence of clinical signs associated with thoracolumbar intervertebral disk herniation in dogs: 229 cases (1994-2000)     

Mayhew PD  McLear RC  Ziemer LS  Culp WT  Russell KN  Shofer FS  Kapatkin AS  Smith GK 《Journal of the American Veterinary Medical Association》2004,225(8):1231-1236

OBJECTIVE: To assess risk factors for recurrence of clinical signs associated with thoracolumbar intervertebral disk disease (IVDD) in dogs that had decompressive laminectomy without attempted prophylactic treatment of other disk spaces. DESIGN: Retrospective study. ANIMALS: 229 dogs. PROCEDURE: Medical records of dogs that had decompressive laminectomy without prophylactic fenestration for a first episode of IVDD and were available for follow-up were reviewed. Information on 7 clinical and 8 radiographic potential risk factors were recorded. RESULTS: Clinical signs associated with recurrence of IVDD developed in 44 (19.2%) dogs. Ninety-six percent of recurrences developed within 3 years after surgery. Recurrence developed in 25% of Dachshunds and 15% of dogs of other breeds combined. Number of opacified disks was a significant risk factor for recurrence. Risk increased with number of opacified disks in an almost linear manner; each opacified disk increased risk by 1.4 times. Dogs with 5 or 6 opacified disks at the time of first surgery had a recurrence rate of 50%. CONCLUSIONS AND CLINICAL RELEVANCE: When all likely episodes of recurrence are considered and a long follow-up period is achieved, true rate of recurrence of IVDD appears to be higher than in many previous reports. Dogs with multiple opacified disks at the time of first surgery should be considered a high-risk subpopulation.  相似文献   

Question diagnostic technique for hip dysplasia     

Smith GK  Biery DN  Kapatkin AS  Laster LL  Powers MY  Fordyce HH  Mayhew PD 《Journal of the American Veterinary Medical Association》2002,220(1):20-1; author reply 21-2

  相似文献   

Evaluation of risk factors for degenerative joint disease associated with hip dysplasia in German Shepherd Dogs, Golden Retrievers, Labrador Retrievers, and Rottweilers.     

G K Smith  P D Mayhew  A S Kapatkin  P J McKelvie  F S Shofer  T P Gregor 《Journal of the American Veterinary Medical Association》2001,219(12):1719-1724

OBJECTIVE: To determine whether age, breed, sex, weight, or distraction index (DI) was associated with the risk that dogs of 4 common breeds (German Shepherd Dog, Golden Retriever, Labrador Retriever, Rottweiler) would have radiographic evidence of degenerative joint disease (DJD) associated with hip dysplasia. DESIGN: Cross-sectional prevalence study. ANIMALS: 15,742 dogs. PROCEDURE: Hips of dogs were evaluated radiographically by use of the ventrodorsal hip-extended view, the compression v ew, and the distraction view. The ventrodorsal hip-extended view was examined to determine whether dogs had DJD. For each breed, a multiple logistic regression model incorporating age, sex, weight, and DI was created. For each breed, disease-susceptibility curves were produced, using all dogs, regardless of age, and dogs grouped on the basis of age. RESULTS: Weight and DI were significant risk factors for DJD in all breeds. For German Shepherd Dogs, the risk of having DJD was 4.95 times the risk for dogs of the other 3 breeds combined. In all breeds, the probability of having DJD increased with age. CONCLUSIONS AND CLINICAL RELEVANCE: Results indicated that the probability of having hip DJD increased with hip joint laxity as measured by use of DI. This association was breed-specific, indicating that breed-specific information on disease susceptibility should be incorporated when making breeding decisions and when deciding on possible surgical treatment of hip dysplasia.  相似文献   

Liver function in normal koalas and macropods     

MA PASS  AS BROWN 《Australian veterinary journal》1990,67(4):151-152

  相似文献   

Atypical scrapie in Australia          下载免费PDF全文

RW Cook  J Bingham  AS Besier  CL Bayley  M Hawes  PL Shearer  M Yamada  J Bergfeld  DT Williams  DJ Middleton 《Australian veterinary journal》2016,94(12):452-455

  相似文献   

Chronic sporidesmin toxicosis and photosensitisation in an alpaca (Vicugna pacos) in New Zealand     

MG Collett  AS Wehrle-Martinez  LK Whitfield  A Kokosinska 《New Zealand veterinary journal》2016,64(5):314-316

  相似文献   

Relationship between endometritis and oxidative stress in the follicular fluid and luteal function in the buffalo          下载免费PDF全文

BK Behera  CG Sharma  SK Singh  H Kumar  RK Chaudhari  AS Mahla  GK Das  N Krishnaswamy 《Reproduction in domestic animals》2016,51(5):844-847

In this study, alteration in the follicular fluid composition and luteal function was investigated in the buffalo with endometritis. Genitalia were classified into cytological and purulent endometritis on the basis of polymorphonuclear cell cut off while non‐endometritis served as control (n = 10/group). In the follicular phase, the number of surface follicles was counted, diameter of the largest follicle was measured and the follicular fluid was assayed for total protein, cholesterol, malondialdehyde (MDA), total antioxidant capacity (TAC), oestradiol (E₂) and progesterone (P₄). The P₄ content of corpus luteum during mid‐luteal phase was estimated by radioimmunoassay. Ovaries from the follicular phase of oestrous cycle showed no significant difference in the total number of surface follicles, size of the largest follicle and volume of follicular fluid in the buffaloes with and without endometritis (p > .05). However, the antral fluid of the largest follicle from the genitalia of buffalo with cytological and purulent endometritis showed a significant decrease in the concentration of total protein, cholesterol, TAC and E₂ and a significant increase in the concentration of MDA and P₄ (p < .05). The results indicated that there is an association between endometritis and decreased ovarian function.  相似文献   

Kinetic gait analysis of healthy dogs on two different surfaces   总被引：1，自引：0，他引：1  

Kapatkin AS  Arbittier G  Kass PH  Gilley RS  Smith GK 《Veterinary surgery : VS》2007,36(6):605-608

Objective— To determine the effects of 2 different, commonly used surfaces with different coefficients of friction on ground reaction forces in normal dogs.
Study Design— Prospective, observational, single cross-over study.
Animals— Dogs (n=10) with no gait abnormalities.
Methods— Dogs were acclimated to the force plate and 5 valid trials for each dog and each limb were recorded. Velocity and acceleration were tightly controlled. Each dog was tested on both surfaces sequentially in different sequences. Data analysis was done on peak vertical force, peak impulse, breaking and propulsion peak forces and impulses. Three-way repeated measures analysis of variance was used to separately evaluate the effect of floor type on force plate measures in fore and hind limbs, while controlling for side (left versus right) and experimental replicate. P -values<.05 were considered significant. Mean force and 95% confidence interval for the 6 variables analyzed for all limbs on each surface were calculated.
Results— There were no significant differences in ground reaction forces between the linoleum and the carpet surface for thoracic or pelvic limbs for all gait variables measured. There were no significant differences between each individual gait trial per dog between the right and left thoracic limbs trials nor differences between the right and left pelvic limb trials.
Conclusions— Normal dogs had no change in their ground reaction forces on linoleum and carpet surfaces.
Clinical Relevance— Kinetic results from multi-center or comparative trials will not be affected by use of either linoleum or carpet surfaces.  相似文献   

Infectious reproductive disease pathogens in dairy herd bulls          下载免费PDF全文

AS Hancock  PJ Younis  DS Beggs  PD Mansell  MF Pyman 《Australian veterinary journal》2015,93(10):349-353

  相似文献   

Intervertebral biomechanics of locking compression plate monocortical fixation of the canine cervical spine     

Agnello KA  Kapatkin AS  Garcia TC  Hayashi K  Welihozkiy AT  Stover SM 《Veterinary surgery : VS》2010,39(8):991-1000

Objective: To evaluate the use of a locking compression plate (LCP) with monocortical screw purchase for stabilization of the canine cervical spine. Study Design: Experimental study. Animals: Cadaveric canine cervical spine specimens (n=7). Methods: Flexion and extension bending moments were applied to canine cadaveric specimens (C3–C6) in 4‐point bending, before and after creation of a ventral slot at C4–C5, and after fixation with a 5 hole, 3.5 mm LCP with monocortical screw placement. Screw placement and penetration into the vertebral canal were determined by radiography. Range of motion, stiffness, and energy for passive physiologic loads were determined for the C3–C4, C4–C5, and C5–C6 vertebral motion units (VMU). Monotonic failure properties were determined for cervical extension. Effects of treatments on biomechanical variables were assessed using repeated measures analysis of variance and least square means (P≤.05). Results: The ventral slot procedure increased range of motion at the treated VMU. Plate fixation decreased range of motion, increased stiffness, and decreased energy at the treated VMU. No changes were observed at adjacent VMUs. None of the screws penetrated the vertebral canal. Mean (± SD) yield bending moment of plate stabilized, slotted spines was 15.6 ± 4.6 N m. Conclusion: LCP fixation with monocortical screws stabilized the canine cervical spine.  相似文献